Enabling early diagnosis and efficient management of neurodegenerative diseases


Healthcare professionals are often overwhelmed with data, making the interpretation challenging in clinical decision making.


cNeuro® from Combinostics gives healthcare professionals a comprehensive view of patient data which helps them to make an early diagnosis of neurodegenerative diseases. 

While there are no effective treatments for neurodegenerative diseases like Alzheimer’s, early-stage diagnosis combined with symptomatic treatment and lifestyle intervention can make a drastic difference to quality of life in later years.


cNeuro® is Combinostics’ cloud platform for quantitative assessment of brain images and for providing clinical decision support in neurological disorders.

cNeuro® has two product modules, cMRI and cDSI.

cNeuro® cMRI

Quantify volumes of 133 brain regions, vascular burden and in the EU, compute medial temporal lobe atrophy (MTA) score, global cortical atrophy (GCA) scale and Fazekas scale.

Compare measures to reference data.

Review results interactively in a web viewer using a standard web browser and obtain a report.

cNeuro® cDSI

Compare neuropsychology, MRI, CSF and genetics measured from your patient to data of previously diagnosed cases.

Quantify the patient’s similarity relative to etiology (AD, FTLD, VaD and cognitive normal) and progression (stable and progressive MCI).

Visualize data in an intuitive way with our patented disease state fingerprint (DSI) technology.

Horizon 2020 project on prevention of cognitive decline

Combinostics joined the EU funded Horizon 2020 project LETHE – A personalized prediction and intervention model for early detection and reduction of risk factors causing dementia, based on AI and distributed Machine Learning (grant agreement No. 101017405,...

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Young outstanding researcher award

Combinostics is collaborating closely with Alzheimercentrum Amsterdam. Because of this, we want to let you know that geriatrician and senior researcher Hanneke Rhodius-Meester from the Alzheimercentrum Amsterdam is nominated for the Young Outstanding Researcher (YOR)...

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